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Topic Contents

Prochlorperazine

Drug Information

Prochlorperazine is used to treat severe nausea and vomiting. It is also used to treat symptoms of psychosis, such as delusions, hallucinations, disorganized thinking and speech, and bizarre behavior. Prochlorperazine is in a class of drugs known as phenothiazines.

Common brand names:

Compazine, Compro

Summary of Interactions with Vitamins, Herbs, & Foods

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

  • none

Reduce Side Effects

  • none

Support Medicine

  • none

Reduces Effectiveness

  • none

Potential Negative Interaction

  • Bacopa

    An animal study found that the effects of chlorpromazine, a drug similar to (perphenazine, prochlorperazine, thioridazine), were enhanced when a bacopa extract was given along with it.1 Until more is known, people taking medications from this family of drugs (called phenothiazines) should not take bacopa.

Explanation Required 

  • none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

References

1. Ganguly DK, Malhotra CL. Some behavioral effects of an active fraction from Herpestis monniera Linn. (Brahmi). Indian J Med Res 1967;55:473–82.

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