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Complementary and Alternative Medicine - Cam

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Topic Contents

Bupropion

Drug Information

Bupropion is used to treat people with depression and to aid in smoking cessation treatment.

Common brand names:

Budeprion XL, Wellbutrin, Zyban, Budeprion SR, Wellbutrin SR, Wellbutrin XL

Summary of Interactions with Vitamins, Herbs, & Foods

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

  • none

Reduce Side Effects

  • none

Support Medicine

  • Yohimbe

    A 50-year-old woman who was unresponsive to traditional antidepressant therapy was reported to have a marked and persistent improvement in mood when yohimbine was added to her bupropion therapy.1 Further research is necessary to determine the significance of this finding.

    The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.

Reduces Effectiveness

  • none

Potential Negative Interaction

  • none

Explanation Required 

  • none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

References

1. Pollack MH, Hamerness P. Adjunctive yohimbine for treatment in refractory depression. Biol Psychiatry 1993;33:220-1.

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