Important It is possible that the main title of the report Multiple Myeloma is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
plasma cell myeloma
plasma cell leukemia
solitary plasmacytoma of bone
Multiple myeloma is a rare form of cancer (1% of malignancy) characterized by excessive production (proliferation) and improper function of certain cells (plasma cells) found in the bone marrow. Plasma cells, which are a type of white blood cell, are produced in the bone marrow and normally reside there. Excessive plasma cells may eventually mass together to form a tumor or tumors in various sites of the body, especially the bone marrow. If only a single tumor is present, the term solitary plasmacytoma is used. When multiple tumors are present, the term multiple myeloma is used. Plasma cells are a key component of the immune system and secrete a substance known as immunoglobulin proteins (M-proteins), a type of antibody. Antibodies are special proteins that the body produces to combat invading microorganisms, toxins, or other foreign substances. Overproduction of plasma cells in affected individuals results in abnormally high levels of these proteins within the body, referred to as M proteins
Major symptoms of multiple myeloma may include bone pain, especially in the back and the ribs; low levels of circulating red blood cells (anemia) resulting in weakness, fatigue, and lack of color (pallor); and kidney (renal) abnormalities. In some cases, affected individuals are more susceptible to bacterial infections such as pneumonia. The cause of multiple myeloma is unknown.
Leukemia & Lymphoma Society 1311 Mamaroneck Avenue Suite 310 White Plains, NY 10605 Tel: (914)949-5213 Fax: (914)949-6691 Tel: (800)955-4572 Email: infocenter@LLS.org Internet: http://www.LLS.org
International Myeloma Foundation 12650 Riverside Drive Suite 206 North Hollywood, CA 91607 USA Tel: (818)487-7455 Fax: (818)487-7454 Tel: (800)452-2873 Email: TheIMF@myeloma.org Internet: http://www.myeloma.org
American Cancer Society, Inc. 250 Williams NW St Ste 6000 Atlanta, GA 30303 USA Tel: (404)320-3333 Tel: (800)227-2345 TDD: (866)228-4327 Internet: http://www.cancer.org
National Cancer Institute 6116 Executive Blvd Suite 300 Bethesda, MD 20892-8322 USA Tel: (301)435-3848 Tel: (800)422-6237 TDD: (800)332-8615 Email: email@example.com Internet: http://www.cancer.gov
NIH/National Heart, Lung and Blood Institute ~ Hematology Branch 10 Center Dr, Building 10-CRC 3-5140, MSC-1202 Bethesda, MD 20892-1202 Tel: (301)496-5093 Fax: (301)496-8396 Tel: (800)644-2337 Email: YoungNS@mail.nih.gov Internet: http://dir.nhlbi.nih.gov/labs/hb/index.asp?
Cancer Research UK Angel Building 407 St John Street London, EC1V 4AD United Kingdom Tel: 020 7242 0200 Fax: 02071216700 Email: firstname.lastname@example.org Internet: http://www.cancerresearchuk.org/cancer-help/
Rare Cancer Alliance 1649 North Pacana Way Green Valley, AZ 85614 USA Internet: http://www.rare-cancer.org
Multiple Myeloma Research Foundation 383 Main Avenue 5th Floor Norwalk, CT 06851 USA Tel: (203)229-0464 Fax: (203)229-0572 Email: email@example.com Internet: http://www.themmrf.org/
Genetic and Rare Diseases (GARD) Information Center PO Box 8126 Gaithersburg, MD 20898-8126 Tel: (301)251-4925 Fax: (301)251-4911 Tel: (888)205-2311 TDD: (888)205-3223 Internet: http://rarediseases.info.nih.gov/GARD/
Patient Registries at Slone: Myeloma & MDS Slone Epidemiology Center 1010 Commonwealth Avenue Boston, MA 02215 Fax: (617)738-5119 Tel: (800)231-3769 Email: firstname.lastname@example.org Internet: http://www.bu.edu/prs
Friends of Cancer Research 1800 M Street NW Suite 1050 South Washington, DC 22202 Tel: (202)944-6700 Email: email@example.com Internet: http://www.focr.org
Cancer.Net American Society of Clinical Oncology 2318 Mill Road Suite 800 Alexandria, VA 22314 Tel: (571)483-1780 Fax: (571)366-9537 Tel: (888)651-3038 Email: firstname.lastname@example.org Internet: http://www.cancer.net/
Cancer Support Community 1050 17th St NW Suite 500 Washington, DC 20036 Tel: (202)659-9709 Fax: (202)974-7999 Tel: (888)793-9355 Internet: http://www.cancersupportcommunity.org/
Lance Armstrong Foundation 2201 E. Sixth Street Austin, TX 78702 Tel: (512)236-8820 Fax: (512)236-8482 Tel: (877)236-8820 Email: email@example.com Internet: http://www.livestrong.org
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This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
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